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Biotechnology4www.lotoriel.co.ukHigh Resolution Optical and Scanning Probe MicrosopesThe WITec microscopy series features scanning probe as well as high resolution optical and Raman microscopy techniques in either a single instrument or combined system con!gurations for the highest "exibility throughout a wide range of microscopy applications.Life Science????????Chemical imaging without the need for "uorescent dyes????????Imaging of cells, tissues and bio-!lmsPharmaceutics, Cosmetics and Food"Industry????????Drug distribution and product homogeneity investigations????????Solid state and foreign particulates analysisFor more information please go to page 36XE-Bio - Non Contact In-liquid Imaging and Ion Conductance MicroscopyThe XE-Bio is a powerful 3-in-1 nanoscience research tool that uniquely combines industry's only True Non-Contact AFM with Ion Conductance Microscopy (ICM) and inverted optical microscope on the same platform. The modular design of the XE-Bio allows easy interchange between non-contact AFM and ICM. Designed for non-invasive in-liquid imaging, the combined imaging capability of AFM, ICM, and inverted optical microscopy makes the XE-Bio ideal for imaging biological samples, such as living cells, in dynamic conditions. Moreover, ICM can be adapted to enable a host of powerful applications in nanoscale electrophysiology.Powerful 3-in-1 Nanoscale Research Tool with Modular PlatformTrue Non-Contact Atomic Force Microscope (AFM)Ion Conductance Microscope (ICM)Inverted Optical MicroscopeUltimate AFM Resolution by True Non-Contact Mode10 times larger Z-scan bandwidth than a piezotubeLess tip wear for prolonged high-quality and high-resolution imagingMinimized sample damage or modi!cationImmunity from parameter-dependent results observed in tapping imaging modeSingle molecule Force-Distance spectroscopy with automated data analysisNon-invasive In-liquid Imaging by ICMMonitoring ion channels of single living cellsUnique functional capability of targeted localized stimulationEnable nanoscale patch-clamping for electrophysiologyEnvironmental chamber for temperature, pH, and humidity controlFully Integrated Inverted Optical MicroscopeCompatible with phase contrast and DIC imagingAlso compatible with "uorescence microscopyAdvanced image overlay functionsWood CellBiotechnology InstrumentationFor other AFMs in the range please go to page 34Human Breast Cancer Cell

Biotechnology5Tweez 200si - A complete turn-key laser tweezers systemTweez is a complete turn-key laser tweezers system designed to !t Nikon Eclipse TE2000/Ti-E microscopes. It combines powerful laser tweezing manipulation capabilities with exceptional stability and accuracy. Tweez is designed for zero maintenance and to let you focus on your application.FeaturesModular design to meet diverse user/application requirements.Fast DSP/FPGA state-of-the-art control system.5 W 1064 nm IR laserUser friendly open architecture software control system.Complex trapping patterns for simultaneous control of over 1000 particles.Up to 4 million user preloaded trapping site patterns.Real-time dynamic trapping pattern morphing.Sub nanometre trap positioning resolution.Up to 100 kHz trap-to-trap switching rate.Typ. 150 #m2 trapping range (depending on the microscope objective).CompactTweez uses acousto-optic (AO) laser beam steering - the only technology capable of sub nanometre optical trap positioning and trap-to-trap switching rates of up to 100 kHz. A unique optics topology is used to pack all optical components into a single ultra stable unit. With a multiwatt IR !bre laser Tweez can achieve a simultaneous control of 1000+ trapped objects.Range of applicationsTweez !nds applications ranging from physics to biology and from fundamental research to industry. The precision and ease-of-use lets you maintain the focus on your project. Advanced I/O and synchronization capabilities along with open software architecture provide custom control for the most demanding setups.